Lbugs: I hope you see this. I've been trying to figure out for a very long time this morning how to troubleshoot the message: "Failed to start up Evernote for Mac" when trying to use my ScanSnap S1300 scanner, which I haven't used in a while. Amazingly, this string of words doesn't even come up in a search of EN. Instead, and as usual, I found a lot of Evernote personnel "help" messages that were snarky and over my head. Thank you, thank you for mentioning the steps you outline above, which finally worked for me, in particular, redownloading FROM WEBSITE.