FWIW... I'm PC & for several years, had my EN database in a Truecrypted container with no issues. Please note that although this worked for me for several years, putting your EN database in a TC container is not supported. ("Not supported" doesn't always translate to "bad". It may just mean "not supported"). Due to another issue (scaling - I apparently have one of the larger EN databases), I've moved my DB out of an encrypted container solely to eliminate all other possible issues when dealing with support on my scaling issue.Just for the record, my local EN database has been living on my Truecrypt encrypted X: drive for many years, on two different Windows PCs. As the drive is therefore not available to my PC until I mount it (and provide the decryption key), Evernote is set (in the Evernote options) NOT to load on PC startup. On my home PC I start it manually. On my work PC I use a desktop switching app (I can't remember the name of it, and I'm not near that PC at the moment to check), and I have that set up to start up all the apps that either live on or have data on the encrypted drive - notably Firefox portable, which is installed on the X: drive, and Evernote, whose data is on the X: drive. To be honest, the issue of supportability never occurred to me, as EN does support you moving your DB to a location of your choice, and Truecrypt is essentially invisible to apps using data on encrypted drives. Of course, all of this only secures your local data. Anybody with your Evernote password (or your email password to request an Evernote password reset) can get access to your data via the EN web app.