AndyinNJ

 Thank you.  This seems to have worked.  I would add to the instructions to choose "Remove Data from This Device" when presented with that choice after Step 1. 

Just downloaded latest Evernote version for Mac, using OS Monterey 12.0.1.  Saved searches based on tags don't pull up notes with those tags, but pull up other tags.  Filtering a list of notes by tags also yields the same issue. If I delete a tag on a note then add the same tag back a saved search or filtering of the list will then work and bring up the note with the tag. Closing and reopening the app didn't work.  Everything seems ok in the web version.

Annotating is working perfectly with my configuration -- Sierra v10.12.3 and Evernote v. 6.10 (454267 direct).  Can annotate on all pdfs, including those previously annotated.

Seems the problem has been fixed! I'm working today with the latest version (6.10) in Sierra and able to annotate normally without any issues. 

I've been regularly and intensely using the workaround recommended by @BSR on Nov 10 and have had no issues using any type of annotation  (Sierra on 13" MacBook Pro mid-2012).  I will be grateful, however, to see normal functionality restored. 

After upgrade to Sierra I'm having the same issues as others.  Temporary workaround for me is to open the pdf within Evernote by clicking on the header.  Since I have Acrobat Pro it opens in that program and I can annotate and save the doc and the annotations are visible in Evernote.  I'm willing to do this for a while until Evernote addresses the issue.