@Alanbarker - I just got a Windows 11 machine, and I'm experiencing the same problem. My Windows 7 and Mac can still do the region capture. Were you able to fix it by any chance? I'd appreciate any ideas you might have. I use this feature more than any other. The Windows snipping tool (ctl + alt + S) is a pain, and doesn't allow direct import into Evernote as I'm sure you've discovered. Thanks!