I have two monitors, both 4K (3840x2160 pixels). On my laptop, the size is 13 inches, so I use a display scaling of 225%. When I'm at my desk and connected to my much larger monitor, I use a display scaling of 125%.
On my 125%-scaled desk monitor I set the EN main window size, as well as the widths of the notebook list pane, the preview pane, and the content pane to my preferences. When I switch to the laptop (225%-scaled), my sizing work is lost. To get EN back to a usable state I must increase the EN main window size vertically and horizontally and widen the notebook list pane.
I go back and forth between my work desk and traveling with my laptop. It's annoying to have to resize EN every time. (BTW EN is the only app that has this issue. Windows' own functions, like file explorer, settings, etc., work fine. MS Office apps, Keepass XC, Encarta, Windows 10 Firewall Control, Adobe Acrobat, Chrome, IE, Firefox... every other program I use works fine.)