This is because we do not fully support hi DPI. In the application, we specifically note we do not in the manifest. So MS auto-scales it up - this is where the blurriness comes from. Yeah, I've had to do this with a few programs in Windows 10, I'm using scaling with a 109 DPI monitor. After changing the DPI settings, if you quit the program, it might stay running in the background. At least that was the case for me with Windows 10. You can Ctl-Alt-Delete > Task Manager > More Details and end task on the Evernote entries (in my case there were 3), then re-launch the program. No need to reboot. Thanks for posting the solution eric99, worked like a charm!