It's even simpeler I think. The setup.exe of version 22.214.171.12436 has an error. On al my pc's the normal installation fails. But the msi installs correctly. You don't have to throw anything away. Just find the msi file in %temp% after the first failed install and run it. Setup.exe runs a command like [03/28/2013 21:27:30] The following arguments will be passed on to msiexec.exe: /lvx* "C:\Users\MyUserName\AppData\Local\Temp\EvernoteSetupMSI.log" /qb ALLUSERS=1 TRANSFORMS=:1043 APPLICATIONFOLDER="C:\Program Files (x86)\Evernote\Evernote\" I think this is a faulty parameter: TRANSFORMS=:1043 So the subset of users for who it fails will probably contain all the people using the dutch language code (1043). Evernote should repair this asap.